ACC Optima (10 Tablets)

Description

ACC Optima is a drug used to reduce airway secretions and facilitate coughing up of secretions in patients with cold-related bronchitis. ACC optima contains the active substance acetylcysteine. Acetylcysteine ​​reduces the viscosity of bronchial secretions and facilitates its expectoration.

Symptoms

ACC optima is indicated as a drug to reduce airway secretions and facilitate its expectoration in patients with cold-related bronchitis.

Active substance: Acetylcysteinum

Composition

Dosage

Adults and adolescents over 14 years of age:

• The daily dose of acetylcysteine ​​is 600 mg (1 ACC optima effervescent tablet once a day).

Method of administration:

ACC optima should be taken after a meal. The effervescent tablet should be dissolved in half a glass of water and drunk immediately after dissolving. Use no later than 4 hours before bedtime. During treatment, it is recommended to drink more fluids. The medicinal product should not be used for more than 4 to 5 days without the recommendation of a physician. If there is no improvement in this time, the patient should contact the doctor.

Contraindications

• Hypersensitivity to acetylcysteine ​​or to any of the excipients.

• Active stomach ulcer or duodenal ulcer.

• Acute asthmatic condition.

• Reduced ability to cough up secretions.

• Pregnancy and the period of breastfeeding.

• Due to the high content of the active substance, ACC optima should not be used in children under the age of 14 years.

Contents

Soft paper / aluminum blister in cardboard box containing 10 effervescent tablets.

Storage method

15°C-25°C

Manufacturer

SANDOZ

Warnings

Acetylcysteine ​​should be used with caution in patients with bronchial asthma (due to the possibility of bronchospasm), in patients with a history of peptic ulcer disease, in the elderly or in respiratory failure. If the simultaneous use of acetylcysteine ​​and oral antibiotics is necessary, these drugs should be taken at least 2 hours apart.

Serious skin reactions such as Stevens-Johnson syndrome and Lyell’s syndrome have been reported very rarely with the use of acetylcysteine. Patients should be advised to stop taking acetylcysteine ​​and seek immediate medical attention if changes to the skin or mucosa occur.

Caution should be exercised in patients with histamine intolerance and avoided long-term treatment in them, as acetylcysteine ​​affects the metabolism of histamine and may cause intolerance symptoms (e.g. headache, vasomotor rhinitis, pruritus).

This medicinal product contains lactose. It should not be used in patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption. The medicinal product contains sodium, which should be taken into account in patients with impaired renal function and in those on a controlled sodium diet.

Information for people with diabetes:

1 effervescent tablet contains less than 0.01 WW.

Pregnancy and lactation

If a woman is pregnant or breastfeeding, thinks she may be pregnant or is planning to have a baby, she should ask her doctor or pharmacist for advice before taking this medicine.

ACC optima should only be used during pregnancy and breastfeeding if your doctor considers it necessary.

Driving vehicles
ACC optima is not known to affect your ability to drive or use machines.

Overdosage

If you take more than the recommended dose of the drug, consult your doctor or pharmacist for advice. Gastrointestinal symptoms such as nausea, vomiting and diarrhea are possible.

Interactions with other drugs

Concomitant use of acetylcysteine ​​and antitussive drugs may cause dangerous discharge due to a reduction in the cough reflex. Such combination therapy requires particularly careful diagnosis.

Tetracycline hydrochloride (except doxycycline) and acetylcysteine ​​should be administered separately with at least a two-hour break.

Existing reports of inactivation of antibiotics by acetylcysteine ​​and other mucolytic drugs refer only to in vitro experiments in which the substances mentioned were mixed together directly. However, for safety reasons, acetylcysteine ​​and orally administered antibiotics should be taken separately, at least 2 hours apart. This does not apply to cefixime and loracarbef.

The described in vitro incompatibilities concerned, in particular, semi-synthetic penicillins, tetracyclines, cephalosporins and aminoglycosides. Acetylcysteine ​​has not been shown to be incompatible with such antibiotics as amoxicillin, doxycycline, erythromycin, thiamphenicol and cefuroxime.

The concomitant use of acetylcysteine ​​and nitroglycerin or other nitrates may lead to an increase in their vasodilating effects and inhibition of platelet aggregation. The clinical significance of this interaction has not yet been elucidated.

Side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

If you develop any of these symptoms, stop using ACC optima and seek medical attention immediately:

• anaphylactic or anaphylactic-like reaction (a type of sudden allergic reaction) with symptoms such as sudden wheezing, difficulty breathing or dizziness, swelling of the eyelids, face, lips or throat, hives, itching;
• angioedema (severe allergic reaction) with swelling of the skin and / or mucous membranes e.g. in the face, limbs, joints
• bronchospasm (sudden shortness of breath).

Uncommon side effects (may affect up to 1 in 100 people):

• hypersensitivity reactions (allergic reactions)
• headache
• Tinnitus
• fast heart beat (tachycardia)
• low blood pressure
• nausea, vomiting, diarrhea, stomach pain
• hives, rash, itching, angioedema
• fever

Rare side effects (may affect up to 1 in 1,000 people):

• indigestion
• shortness of breath, bronchospasm

Very rare side effects (may affect up to 1 in 10,000 people):

• anaphylactic or anaphylactic-like reaction up to anaphylactic shock
• haemorrhage

Not known side effects (frequency cannot be estimated from the available data):

• swelling of the face