Zimgi Cosmetics

Aspargin

Aspargin tablets help to replenish magnesium and potassium deficiencies in the body.

The drug Aspargin contains a well-absorbed mixture of magnesium and potassium salts of aspartic acid, which is an important building component of the body. Magnesium and potassium work closely together in many physiological processes:

Magnesium performs numerous metabolic functions, is an activator of many enzymes, mediates in the production and transport of energy in the body. It is essential in the activity of the heart muscle, nervous system, vascular smooth muscle and striated muscles. Magnesium deficiency increases the risk of coronary artery disease, heart attack and arrhythmias.

Symptoms of magnesium deficiency are:

• Hyperactivity,
• Difficulty concentrating and sleeping,
• Increased susceptibility to stress,
• Disorders of the skeletal muscles, manifested by their tremors, cramps and the so-called tics.

Potassium participates in the activity of the nervous system and the cardiovascular system as well as in neuromuscular conduction.

Potassium deficiency poses a threat to the proper functioning of:

• Nervous system, nerve and neuromuscular conduction (movement, heart work, functioning of other internal organs),
• A system that transports various substances from and to the cells of the body (nutrition, respiration and excretion),
• The circulatory and excretory systems in the regulation of water and electrolyte management (responsible for maintaining proper blood pressure and acidity). Aspartic acid is involved in the transmission of stimuli in the central nervous system.

Aspargin has the status of an OTC drug – a drug dispensed without a doctor’s prescription, without a prescription.

Intended Use

Supplementing magnesium and potassium deficiency (not requiring intravenous administration of elements):

• With arrhythmias and overexcitability of the heart, especially against the background of magnesium and potassium deficiency,
• Prophylactically in ischemic heart disease, at risk of myocardial infarction,
• In post-infarction convalescence,
• After infectious diseases or surgical procedures during which there was a loss of magnesium and potassium,
• As a drug counteracting the undesirable effects of long-term use of cardiac glycosides and diuretics (e.g. thiazides, furosemide).

Aspargin is intended for patients over 12 years of age.

Active substance: Kalii hydrogenoaspartas, Magnesii hydrogenoaspartas

Composition

The active substances of Aspargin are: magnesium hydrogen aspartate and potassium hydrogen aspartate.

1 tablet contains 17 mg of magnesium ions in the form of 250 mg of magnesium hydrogen aspartate; 54 mg of potassium ions in the form of 250 mg of potassium hydrogen aspartate.

Excipients: potato starch, sodium carboxymethyl starch, sucrose, magnesium stearate, talc.

Dosage

The usual dose is 1 to 2 tablets orally 2 to 3 times a day, after meals, i.e. 2 to 6 tablets a day in 2 or 3 divided doses, corresponding to 108 mg to 324 mg potassium per day and 34 mg to 102 mg of magnesium per day.

Aspargin should be taken after a meal with water.

The drug should not be used in children under 12 years of age

When should Aspargin not be used?

If you may experience:

• Hypersensitivity to any component of the medicinal product,
• Hypermagnesemia,
• Hyperkalemia,
• Severe renal failure (creatinine clearance less than 30 ml/min),
• Urinary tract infections,
• Atrioventricular conduction disorders (block),
• Bradycardia, myasthenia gravis ,
• Severe hypotension.

Contents

A pack of Aspargin contains 75 tablets and a package leaflet.

Storage method

Below 25°C

Manufacturer

FILOFARM

Warnings

This is medicine. For safety, use it according to the leaflet attached to the package. Do not exceed the maximum dose of the drug. If in doubt, consult your doctor or pharmacist.

• Do not administer without the doctor’s knowledge in cancer diseases.
• The medicinal product should not be used in acute dehydration, extensive tissue destruction (e.g. burns of large body surfaces).
• Do not administer with other preparations containing potassium.
• With long-term use, in the event of severe diarrhea and in patients treated with cardiac glycosides, the concentration of potassium and magnesium in the serum and, if necessary, also in the erythrocytes should be monitored.
• Use with caution in patients with gastric ulcer.
• Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase isomaltase insufficiency should not take this medicinal product.

During pregnancy and breastfeeding
If you are pregnant or breast-feeding, think you may be pregnant or are planning to become pregnant, ask your doctor or pharmacist for advice before taking any medicine.

Aspargin and the use of other drugs
Do not use Aspargin together with the following medicines:

• Tetracycline antibiotics, as magnesium salts reduce the absorption of these antibiotics; there should be at least a 3-hour interval between administration of these drugs;
• Oral anticoagulants coumarin derivatives, fluoroquinolones, fluoride;
• Drugs and dietary supplements containing phosphates, calcium and iron, as magnesium reduces their absorption;
• Atropine or hyoscyamine, as the risk of intestinal ulceration, which may occur with oral intake of potassium salts, increases.

Digitalis glycosides (heart medicines) used in combination with potassium may lead to heart rhythm disturbances. Diuretics (amiloride, spironolactone, triamterene) and angiotensin converting enzyme inhibitors (drugs used in cardiovascular diseases, e.g. captopril and enalapril) cause an increase in potassium levels in the blood. Aminoglycoside antibiotics, loop diuretics, cisplatin, cycloserine, mithramycin, amphotericin B and mineralocorticoids increase magnesium excretion. Cortisone reduces the effects of potassium. The potassium contained in the drug reduces the absorption of vitamin B12.

Side Effects

Uncommon (symptoms occur in less than 1 in 100 patients treated):

• stomach pain,
• nausea,
• diarrhea,
• constipation,
• vomiting, which usually goes away on its own.

Rare side effects (occur in 1 to 10 out of 10,000 patients treated):

• atrioventricular conduction disorders (heart disorders),
• muscle weakness,
• redness of the skin.

Rarely, especially in people with impaired kidney function:

• hyperkalemia.

Very rare side effects (affect less than 1 in 10,000
patients treated):

• insomnia.

If you experience severe side effects, please contact your doctor.
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet.