Radirex (10 Tablets)
Radirex has been used traditionally as a laxative for constipation.
Active substance: Rhei radix
Rhei radix pulveratum – 513.5 mg
Orally: adults and children over 12 years of age 2 tablets once, preferably at bedtime. If necessary, the dosage can be increased to 3 tablets a day.
The most appropriate individual dose is the lowest dose needed to produce a soft stool.
The laxative effect occurs after 6-8 hours.
Hypersensitivity to any of the ingredients of the preparation, intestinal obstruction, intestinal atony, acute and chronic inflammatory bowel diseases (including ulcerative colitis, Crohn’s disease), appendicitis, hemorrhoids, glomerulonephritis, oxalate stones, diarrhea, dehydration and electrolyte disturbances; and abdominal pain of unclear etiology.
Pregnancy and breastfeeding. Children under 12 years of age.
Radirex are brown, round, biconvex tablets. The unit package is a cardboard box containing 1 or 2 Al./PVC foil blisters of 10 tablets.
As with all laxatives, Radirex should not be given if you have any undiagnosed symptoms of acute or persistent abdominal pain.
If it is necessary to take laxatives daily, then you should have a specialist investigate the causes of constipation. Long-term use of laxatives should be avoided. Medical supervision is necessary in the case of treatment with these drugs lasting more than 2 weeks. Chronic use may result in the deposition of pigments in the intestinal mucosa (pseudomelanosis coli) – however, this phenomenon is harmless and disappears after discontinuation of the drug. Overuse of Radirex leading to loss of fluid and electrolytes may be addictive due to the need to take increased doses of the drug in order to obtain a laxative effect. Overuse may disturb the functioning of the colon (atony). Long term use of laxatives containing anthranoids may make constipation worse. Hypokalaemia can lead to cardiac disorders and neuromuscular disorders, especially when taken concomitantly with cardiac glycosides, diuretics or corticosteroids. Chronic use may lead to proteinuria and haematuria.
The use of stimulant laxatives for chronic constipation cannot replace the need to change your diet.
Avoid using the drug during menstruation.
Pregnancy and breastfeeding
The safety of the drug has not been studied in pregnant and lactating women. Do not use the drug during pregnancy and breastfeeding.
The drug does not impair psychophysical fitness, the ability to drive vehicles and operate moving mechanisms.
Overdose may cause rapid diarrhea leading to fluid and electrolyte disturbances with the usual sequelae such as heart rhythm disturbances, muscle weakness. In the event of an overdose, the fluid and electrolytes in the body should be balanced.
Interactions with other drugs
The effect of cardiac glycosides may be intensified in the case of a decrease in the level of potassium caused by the abuse of feeding preparations. Lowering the potassium level may affect the action of simultaneously used antiarrhythmic drugs and cardiac glycosides. Concomitant use of diuretics, adrenal cortex steroids or licorice root can increase potassium loss.
Usually no side effects are observed. Rarely, allergic reactions to the ingredients of the medication, diarrhea, hypokalemia, cramps and abdominal pain may occur, especially in patients with irritable bowel syndrome. Metabolite induced yellow or reddish brown (depending on pH) color of urine is clinically insignificant.