Zovirax Duo contains two active substances: acyclovir and hydrocortisone, which help combat the Herpes simplex virus.

  • Aciclovir is antiviral and helps fight the virus that causes herpes.
  • Hydrocortisone is a mild steroid to reduce the inflammation associated with cold sores.

Herpes simplex is caused by the herpes simplex virus. This virus causes blisters and sores, mostly on the lips but also on other parts of the face. Cold sores can develop when the body’s immune system is weakened, for example during a cold or other infection. Stress, strong sunlight, cold temperatures, or your period can also trigger cold sores.


Zovirax Duo cream is used:

  • to treat early signs and symptoms of cold sores on the lips and skin around the mouth (such as tingling, itching or redness) to reduce the risk of developing cold sores in adults and adolescents 12 years and older.

Even if the cold sores have blistered, treatment with Zovirax Duo reduces the healing time of lesions by about half to a day compared to a cream that does not contain active substances.

If symptoms persist 5 days after stopping treatment, you should see your doctor.

Active substance: Aciclovirum, Hydrocortisonum

Active substances The active substances of the drug are acyclovir and hydrocortisone.

One gram of cream contains 50 mg of aciclovir and 10 mg of hydrocortisone.

the other ingredients liquid paraffin, white petrolatum, isopropyl myristate, sodium lauryl sulfate, cetostearyl alcohol, poloxamer 188, propylene glycol, citric acid monohydrate, sodium hydroxide, hydrochloric acid, purified water.

Zovirax Duo is for external use only.

Do not use more than the recommended dose.

Use in adults and children over 12 years of age:

  • Apply the drug 5 times a day for 5 days (on average every 3-4 hours during the day). It is recommended to start treatment as soon as possible, preferably when the first signs of cold sores (such as tingling, redness or itching) appear.
  • Do not use the drug for more than 5 days.
  • The patient must see a doctor if herpes symptoms persist for more than 5 days after stopping treatment.

You should wash your hands before and after applying the cream to avoid getting any worse herpes or infecting another person.

If an ulcer develops, you should not touch the area more often than necessary so as not to spread the infection to other parts of the body or to the eyes.

Use of the drug in children and adolescents
Do not use this medicine in children under 12 years of age, as its effectiveness and safety in this age group are not known.


Do not use Zovirax Duo

  • if you are allergic to acyclovir, valaciclovir, hydrocortisone, or any of the other ingredients of this medicine.
  • for skin infections not caused by the virus that causes herpes.


Zovirax Duo is a white cream.

The packaging of the drug is an aluminum tube or HDPE laminated aluminum tube containing 2 g of cream, placed in a cardboard box.

Storage method



Only use Zovirax Duo on cold sores on the lips and skin around the mouth.

Talk to your doctor about severe recurrent cold sores to see if you have any other health problems.

Do not use Zovirax Duo:

  • in the eyes, inside the mouth, in the nose or genitals,
  • in the treatment of genital herpes,
  • if you have a weakened immune system, e.g. you have had a bone marrow transplant or you are HIV positive, or you have been diagnosed with an immune system disorder,
  • together with dressings such as dressings or herpes patches.

Hands should be washed before and after applying the medicine, in order to avoid worsening of the disease or spreading it to others.

Contact your doctor if you experience blurred vision or other visual disturbances.

Do not use the drug for more than 5 days.

  • Zovirax Duo contains propylene glycol and cetostearyl alcohol.Propylene glycol may cause skin irritation. Cetostearyl alcohol can cause local skin reactions (e.g. contact dermatitis).
  • Zovirax Duo contains sodium laurilsulfateThe drug contains 8 mg of sodium lauryl sulfate in 1 g of cream, which corresponds to 0.8% w / w.Sodium lauryl sulfate may cause local skin reactions (such as stinging or burning sensation) or may aggravate skin reactions caused by other products applied to the same area.

Pregnancy and breastfeeding
If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. Zovirax Duo should not be used during pregnancy and breastfeeding unless the doctor considers that the benefit to the mother outweighs the unknown risk.

Driving vehicles
Zovirax Duo has no influence on the ability to drive and use machines.

If a patient accidentally applies too much cream or swallows it, it is unlikely to cause any health problems. However, if a large amount of the cream is swallowed, consult a doctor. If you have any questions about the use of this medicine, ask your doctor or pharmacist.

Interactions with other drugs
Tell your doctor about all the medicines you are taking, or have recently taken, and about any medicines you plan to take, including over-the-counter medicines. It is not known if the effect of Zovirax Duo may be changed if you are taking other medicines at the same time.

Side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Stop using the medicine immediately and contact your doctor if you experience any of the following symptoms of an allergic reaction (very rare side effects: may affect up to 1 in 10,000 people):

  • swelling of the face, tongue or throat which may cause difficulty in swallowing or breathing.
  • hives.

Side effects are listed below in order of likelihood of experiencing them:

Common: may affect up to 1 in 10 people

  • Dryness and peeling of the skin.

Uncommon: may affect up to 1 in 100 people

  • Temporary burning, tingling or prickling that may occur immediately after applying the cream.
  • Itch.

Rare: may affect up to 1 in 1,000 people

  • Signs of inflammation such as swollen lips
  • Erythema
  • Disturbances in skin color

Not known:

  • blurred vision

If you get any side effects, talk to your doctor or pharmacist, including any side effects not listed in this leaflet.

Weight 0.5 oz
Dimensions 4 × 3 × 2 in


Made In

Active Substances


Availability Now available in-store at
4604 New Utrecht Ave Brooklyn 11219

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Zovirax Duo 2g


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